Search results for " Transglutaminase antibody"

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Correlation between IgA tissue transglutaminase antibody ratio and histological finding in celiac disease.

2011

OBJECTIVES: Positivity of both immunoglobulin A anti-tissue transglutaminase (TTG) and anti-endomysium antibodies (EMA) has a positive predictive value of nearly 100% for celiac disease (CD). The objective of the present study was to evaluate whether patients of any age, with high pretest probability of CD and high titre of anti-TTG and EMA positivity, have a high probability of intestinal damage and may not require the biopsy for final diagnosis. METHODS: A retrospective analysis of 412 consecutively referred patients, age range 10 months to 72 years, who underwent small-bowel biopsy for suspicion of CD and positivity to both anti-TTG and EMA, was performed at 4 Italian centers. Biopsies w…

Immunoglobulin AAdultMalemedicine.medical_specialtyPathologyAdolescentTissue transglutaminaseDuodenumBiopsySettore MED/08 - Anatomia PatologicaGastroenterologySeverity of Illness IndexCoeliac diseaseStatistics NonparametricYoung AdultCoeliac disease Transglutaminase antibodyGTP-Binding ProteinsPredictive Value of TestsInternal medicineSeverity of illnessBiopsymedicineHumansProtein Glutamine gamma Glutamyltransferase 2ChildAgedRetrospective StudiesSettore MED/12 - GastroenterologiaTransglutaminasesbiologymedicine.diagnostic_testbusiness.industryMusclesGastroenterologyInfantRetrospective cohort studyMiddle Agedmedicine.diseaseImmunoglobulin APre- and post-test probabilityCeliac DiseaseLogistic ModelsPredictive value of testsChild PreschoolPediatrics Perinatology and Child Healthbiology.proteinFemalebusinessJournal of pediatric gastroenterology and nutrition
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